Naltrexone aka Naltima 50mg (Buy Naltrexone online) is an opioid receptor antagonist used primarily in the management of alcohol dependence and opioid dependence. It is marketed in generic form as its hydrochloride salt, naltrexone hydrochloride, and marketed under the trade names Revia and Depade. In some countries including the United States, a once-monthly extended-release injectable formulation is marketed under the trade name Vivitrol. Also in the US, Methylnaltrexone Bromide, a closely related drug, is marketed as Relistor, for the treatment of opioid induced constipation. (Get Naltrexone Cash on delivery)
Naltrexone should not be confused with naloxone (which is used in emergency cases of opioid overdose) nor nalorphine. Using naloxone in place of naltrexone can cause acute opioid withdrawal symptoms; conversely, using naltrexone in place of naloxone in an overdose can lead to insufficient opioid antagonism and fail to reverse the overdose.
How Does Naltrexone or Naltima Work?
For people who have stopped drinking, Naltima (Naltrexone) reduces the craving for alcohol which many alcohol dependent people experience when they quit drinking. It is not fully understood how Naltima works to reduce the craving for alcohol, but some scientists believe it works by affecting the neural pathways in the brain where the neurotransmitter dopamine is found.
For those who are addicted to opioids, Naltrexone works by blocking the effects of drugs like heroin and cocaine in the brain. As an opioid receptor antagonist, Naltrexone simply blocks the normal reaction of the part of the brain that produces the feeling of pleasure when opioids are taken. (Buy Naltrexone Online with COD option)
The main use of naltrexone is for the treatment of alcohol dependence. Naltrexone was approved for the treatment of alcohol dependence in 1994, following publication of the first two randomized, controlled trials in 1992. Since then a number of studies have confirmed its efficacy in reducing frequency and severity of relapse to drinking. The multi-center COMBINE study showed the usefulness of naltrexone in a primary care setting, without adjunct psychotherapy.
The standard regimen is one 50 mg tablet per day.
Naltrexone has been shown to reduce relapse rates after abstinence in multiple clinical studies. Additionally there is evidence that naltrexone helps reduce heavy drinking when used in people who continue drinking while taking naltrexone. Some authors argue that naltrexone may be more effective when used during active drinking than in abstinence, termed the Sinclair Method.
Naltrexone/Naltima helps patients overcome opioid addiction by blocking the drugs’ euphoric effects. Unlike when used for alcohol dependence (discussed above), Naltrexone has little effect on opioid cravings. Naltrexone has in general been better studied for alcohol dependence than in treating opioid dependence. It is also more frequently used for alcohol, despite originally being approved by the FDA in 1984 for opioid addiction.
A recent review of studies suggests that more research is needed to show naltrexone’s effectiveness in treating opioid dependence (and to compare naltrexone to other options such as methadone and buprenorphine). While some patients do well with the oral formulation, there is a drawback in that it must be taken daily, and a patient whose cravings become overwhelming can obtain opioid intoxication simply by skipping a dose before resuming abuse. Due to this issue, the usefulness of oral naltrexone in opioid dependence is limited by the low retention in treatment. Oral naltrexone remains an ideal treatment only for a small part of the opioid-dependent population, usually the ones with an unusually stable social situation and motivation (e.g., dependent health care professionals). Naltrexone treats the physical dependence on opioids, but further psychosocial interventions (such as counselling and group therapy) are often required to enable people to maintain abstinence. Order Natima online now and Purchase Naltima 50mg cash on delivery.